Overview

New sequencing technologies are currently revolutionizing the field of genomic diagnostics. They enable geneticists to investigate exomes, genomes and transcriptomes at an unexampled depth and level of detail.
The availability of comprehensive genetic services locally:

  • will avoid an uncertainty for families, not to mention the economic costs of unnecessary diagnostic procedures
  • improve patient’s management by clinicians.
  • improve prophylactic strategies for patients
  • will reduce the cost be approximately 50% comparing to the price offered by international laboratories.
  • will address local concerns about privacy and exporting genetic data for commercial purposes - confidentiality of results

Molecular Genetics Laboratory

The Genomics Core Facility in GENETIKA laboratory is well equipped with state-of-the-art technologies for functional genomics
analysis and operated by highly qualified staff.

GENETIKA laboratory provides its services to a broad range of users ranging from small research groups to clinical organizations. The complete process of genomics operations ,interpretation and data analysis are carried out in-house in our laboratory facility situated in Dubai, UAE which accomplishes faster TAT for various applications Our facility is equipped with Ion Torrent S5 XL Next Generation Sequencing platform .Importantly, the utmost priority in regard to the confidentiality of each patient’s data records is maintained by in-house based Ion Reporter Server for various applications like Exome, PGS, Targeted panel etc. data analysis and storage. We have well established in house Non-Invasive Prenatal Screening (done during pregnancy to rule out various chromosomal abnormalities) test present locally with acquisition of a complete CE-IVD setup which includes presence of Ion A workstation for data analysis and reporting.

Some of the various genomic solutions provided by GENETIKA laboratory include Exome, PGS, Targeted panel, Carrier screening panel, PGD, NIPT, Y-chromosome deletion analysis etc. which are vital tools for safer and healthier community outcomes done during various steps like Pre-marital screening, Pre-Pregnancy, Pre-IVF, During IVF process etc.

The various genomic applications provided by a robust instrumentation infrastructure (e.g. IONS 5XL system, ION CHEF system, IONA work station, RT-PCR platform, Automatic DNA extraction system, Bioanalyzer, Fragment Analyzer, and more). In well planned laboratory set up having dedicated rooms for DNA Extraction, Pre-PCR, Post PCR activities. The laboratory workflow is highly maintained within the defined standards including maintenance of different pressure levels-controlled systems in each designated area within the lab from the time of receiving the sample till the completion of test process. Thus, enabling us to produce accurate test results with reduced TAT in highest level of contamination free maintained environment.

Our Laboratory

Genetika is located inside MenaLabs Dubai HUB platform formally named Clinical Pathology Services on Umm Suqeim Road. The Laboratory is divided in four rooms to prevent any type of cross contamination. One is dedicated to DNA extraction, one to PCR preparation, one to DNA sequencing and post PCR, the final room is solely used for data analysis.


Technology:

Exome Panel
Targets >97% of CCDSs with 5 bp padding around exons
Primer pool size ~294,000 primer pairs across 12 primer pools
Input DNA required per sample 50–100 ng
Time-to-results 5 days from DNA to variants
Ion S5 System Ion ReproSeq™ PGS Kits for the Ion S5™
Detection of aneuploidies across all 24 chromosomes (22 autosomes and the X and Y chromosomes).

Turn Around Time
Being in Dubai we provide faster TAT than any sample shipped abroad.
Minimum and Maximum TAT for each test can be found in the catalog.


Premaitha Health plc

Premaitha Health is an international molecular diagnostics group which uses the latest advances in DNA analysis technology to develop safer, faster and regulatory approved genetic screening tests. The Group’s primary focus is on non-invasive prenatal tests (NIPT) for pregnant women. Premaitha’s IONA® test was launched in 2015 as the first CE-IVD NIPT test in Europe. It enables laboratories and healthcare practitioners to offer a complete CE-marked NIPT system in-house. The IONA® test is performed on a maternal blood sample – which contains traces of fetal DNA – and estimates the risk of a fetus being affected with Down’s syndrome or other genetic conditions. After a thorough evaluation, MenaLabs has decided to select the IONA test as its NIPT solution. Under the agreement MenaLabs will become the regional platform of Premaitha Health to provide NIPT testing with the highest quality and with the shorter turn around time.